Acute generalized exanthematous pustulosis due to oral use of blue dyes

• Published in: The Korean journal of internal medicine Vol. 26; no. 3; pp. 360 - 363
• Main Authors: Sener, Osman, Kose, Ösman, Kartal, Özgür, Safali, Mukerrem
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Association of Internal Medicine 01.09.2011; 대한내과학회
• Subjects: Acute Generalized Exanthematous Pustulosis - chemically induced; Acute Generalized Exanthematous Pustulosis - drug therapy; Acute Generalized Exanthematous Pustulosis - pathology; Administration, Oral; Adrenal Cortex Hormones - therapeutic use; Aged; Biopsy; Case Report; Coloring Agents - administration & dosage; Coloring Agents - adverse effects; Humans; Indigo Carmine; Indoles - administration & dosage; Indoles - adverse effects; Intradermal Tests; Male; Methylene Blue - administration & dosage; Methylene Blue - adverse effects; Skin - drug effects; Skin - pathology; Treatment Outcome; 내과학; Indigofera; Drug eruptions; Methylene blue
• ISSN: 1226-3303; 2005-6648
• DOI: 10.3904/kjim.2011.26.3.360

Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.