An adolescent with large cell calcifying sertoli cell tumor of the testis and undiagnosed Carney Complex: A case report

• Published in: Diagnostic cytopathology Vol. 45; no. 7; pp. 634 - 639
• Main Authors: Rosenblum, Frida, Koenig, Richard Gabriel, Mikhail, Fady M., Porterfield, John R., Nix, Jeffrey W., Eltoum, Isam‐Eldin A.
• Format: Journal Article
• Language: English
• Published: United States Wiley Subscription Services, Inc 01.07.2017
• Subjects: Adrenal Gland Neoplasms - diagnosis; Adrenal Gland Neoplasms - genetics; Adrenal Gland Neoplasms - pathology; Adrenal Gland Neoplasms - surgery; Adrenalectomy; Calcification; Carney complex; Carney Complex - diagnosis; Carney Complex - genetics; Carney Complex - pathology; Carney Complex - surgery; Case reports; Cyclic AMP-Dependent Protein Kinase RIalpha Subunit - genetics; cytology; Gene Expression; Humans; Literature reviews; Male; Mutation; Nephrectomy; Orchiectomy; Pancreatectomy; Reviews; Sertoli Cell Tumor - diagnosis; Sertoli Cell Tumor - genetics; Sertoli Cell Tumor - pathology; Sertoli Cell Tumor - surgery; Splenectomy; Testicular Neoplasms - diagnosis; Testicular Neoplasms - genetics; Testicular Neoplasms - pathology; Testicular Neoplasms - surgery; Testis - pathology; Testis - surgery; Young Adult; cytology; Carney complex
• ISSN: 8755-1039; 1097-0339
• DOI: 10.1002/dc.23700

Carney Complex (CNC) is a rare autosomal dominant condition with characteristic clinical presentation, tumor development, and unique genetic mutation. We present a unique case and literature review of CNC in which two neoplasms characteristic of this complex were initially diagnosed through cytological fine needle aspirate specimens, leading to the identification of CNC, with subsequent surgical and cytogenetic confirmation. Diagn. Cytopathol. 2017;45:634–639. © 2017 Wiley Periodicals, Inc.