Mouse chromosome 2
Nearly 1400 markers are now shown on the on-line version of the Chr 2 map. These include genes, anonymous sequences and chromosome aberrations. Fifty-one new genes and 7 new quantitative trait loci (QTL) have been added since the last report. Thirty-five visible mutants map to Chr 2, including one n...
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| Published in | Mammalian genome Vol. 10; no. 10; p. 941 |
|---|---|
| Main Authors | , , , |
| Format | Journal Article |
| Language | English |
| Published |
United States
Springer Nature B.V
01.10.1999
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Nearly 1400 markers are now shown on the on-line version of the Chr 2 map. These include genes, anonymous sequences and chromosome aberrations. Fifty-one new genes and 7 new quantitative trait loci (QTL) have been added since the last report. Thirty-five visible mutants map to Chr 2, including one new one, itchy (Itch), with an immunological phenotype. Itch encodes a novel E3 ubiquitin protein ligase, a protein involved in ubiquitin mediated protein degradation (45910). The wst mutation, which leads to a fatal wasting, immunological and neurological disorder, was shown to be a deletion of eukaryotic translation factor 1 alpha 2 (47466). In 1998 two historically significant autosomal transplantation antigen genes H13 and H3a, originally described by Snell in 1958 (Snell, G.D. (1958) J.Natl. Cancer Inst. 21: 843-877) as part of the first ever set of congenics, were cloned (43690, 51335). |
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| AbstractList | Nearly 1400 markers are now shown on the on-line version of the Chr 2 map. These include genes, anonymous sequences and chromosome aberrations. Fifty-one new genes and 7 new quantitative trait loci (QTL) have been added since the last report. Thirty-five visible mutants map to Chr 2, including one new one, itchy (Itch), with an immunological phenotype. Itch encodes a novel E3 ubiquitin protein ligase, a protein involved in ubiquitin mediated protein degradation (45910). The wst mutation, which leads to a fatal wasting, immunological and neurological disorder, was shown to be a deletion of eukaryotic translation factor 1 alpha 2 (47466). In 1998 two historically significant autosomal transplantation antigen genes H13 and H3a, originally described by Snell in 1958 (Snell, G.D. (1958) J.Natl. Cancer Inst. 21: 843-877) as part of the first ever set of congenics, were cloned (43690, 51335). |
| Author | Selley, R Zuberi, A R Peters, J Church, D |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10501944$$D View this record in MEDLINE/PubMed |
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| SubjectTerms | Animals Chromosome Mapping Chromosomes - genetics Chromosomes, Artificial, Yeast - genetics Crosses, Genetic Genetic Markers Humans Mice Mutation |
| Title | Mouse chromosome 2 |
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