Phylogenetic insight of Nonribosomal peptide synthetases (NRPS) Adenylate domain in Antibacterial potential Streptomyces BDUSMP 02 isolated from Pitchavaram Mangrove

Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-d...

Full description

Saved in:
Bibliographic Details
Published inBioinformation Vol. 15; no. 6; pp. 412 - 418
Main Authors Sivalingam, Periyasamy, Muthuselvam, Manickam, Pote, John, Prabakar, Kandasamy
Format Journal Article
LanguageEnglish
Published Singapore Biomedical Informatics 2019
Subjects
Antibacterial materials
Bioactive compounds
Gene clusters
Metabolites
Phylogeny
Streptomyces
Streptomyces
NRPS
adenylate domain
Phylogeny
Mangrove
Online AccessGet full text

Cover

More Information
Summary:Identification of gene clusters in Streptomyces holds promise for the discovery of regulatory pathways linked to bioactive metabolites. We isolated a broad-spectrum antibacterial potential Streptomyces sp BDUSMP 02 from mangrove sediment. We further found a distinct of phylogeny pattern for NRPS A-domain in the Streptomyces sp BDUSMP 02. The result suggests that Streptomyces sp BDUSMP 02 has the potential to produce a new type of antibacterial compounds belonging to NRPS type.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
ISSN:0973-2063
0973-8894
0973-2063
DOI:10.6026/97320630015412