Intravascular ultrasound for evaluation of portal venous involvement in pancreatic cancer

• Published in: European radiology Vol. 7; no. 1; pp. 21 - 25
• Main Authors: Hannesson, P H, Stridbeck, H, Lundstedt, C, Dawiskiba, S, Andrén-Sandberg, A, Ihse, I
• Format: Journal Article
• Language: English
• Published: Germany Springer Nature B.V 1997
• Subjects: Aged; Aged, 80 and over; Carcinoma; Catheters; Female; Head; Humans; Male; Middle Aged; Neoplasm Invasiveness; Pancreas; Pancreatic cancer; Pancreatic Neoplasms - diagnostic imaging; Pancreatic Neoplasms - pathology; Pancreatic Neoplasms - surgery; Portal vein; Portal Vein - diagnostic imaging; Portal Vein - pathology; Portal Vein - surgery; Sensitivity and Specificity; Surgery; Ultrasonography, Interventional - methods; Ultrasound; Veins & arteries
• ISSN: 0938-7994; 1432-1084
• DOI: 10.1007/s003300050101

The aim of this study was to evaluate the accuracy of intravascular ultrasound (IVUS) in diagnosing tumour involvement of the portal vein in patients with exocrine cancer of the head of the pancreas. Seven consecutive patients with a preoperative diagnosis of carcinoma, preoperatively deemed to be resectable, were examined with IVUS of the portal vein during surgery. The IVUS catheters were 6.2 F (2.0 mm) in diameter with a 20-MHz transducer and were introduced into the portal vasculature through the mesenteric superior vein. All patients had tumour extending to the portal vein as demonstrated at histopathological examinations in six cases and at surgical dissection in one case. The IVUS technique correctly identified all these patients, whereas five patients were incorrectly deemed at surgery not to have tumour involvement of the portal vein. These results indicate that IVUS is a very sensitive method for the evaluation of tumour involvement of the portal vein.