Chromosome Biology: The Sight of DNA, at Last

Chromosomes are shaped by the combined function of the condensin and cohesin Smc-kleisin complexes. After more than two decades of research in this field, a new study finally sheds light on how these machines might interact with their DNA substrates. Chromosomes are shaped by the combined function o...

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Bibliographic Details
Published inCurrent biology Vol. 28; no. 2; pp. R77 - R79
Main Author Gligoris, Thomas G.
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 22.01.2018
Subjects
Adenosine Triphosphatases
Cell Cycle Proteins - genetics
Chromosomal Proteins, Non-Histone
Chromosomes
DNA
DNA-Binding Proteins - genetics
Multiprotein Complexes
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Summary:Chromosomes are shaped by the combined function of the condensin and cohesin Smc-kleisin complexes. After more than two decades of research in this field, a new study finally sheds light on how these machines might interact with their DNA substrates. Chromosomes are shaped by the combined function of the condensin and cohesin Smc-kleisin complexes. After more than two decades of research in this field, a new study finally sheds light on how these machines might interact with their DNA substrates.
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ISSN:0960-9822
1879-0445
DOI:10.1016/j.cub.2017.11.066