Post-translational regulation of FOXO

• Published in: Acta biochimica et biophysica Sinica Vol. 44; no. 11; pp. 897 - 901
• Main Authors: Xie, Qi, Chen, Jing, Yuan, Zengqiang
• Format: Journal Article
• Language: English
• Published: China 01.11.2012
• Subjects: Acetylation; Forkhead Transcription Factors - metabolism; Glycosylation; Humans; Methylation; Phosphorylation; Protein Processing, Post-Translational; Ubiquitination; 家族; 应激性; 生物学功能; 细胞周期; 细胞死亡; 翻译后修饰; 调控; 转录因子

The Forkhead box O （FOXO） family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post- translational modifications, which are closely related to their...