Post-translational regulation of FOXO

The Forkhead box O （FOXO） family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post- translational modifications, which are closely related to their...

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Published inActa biochimica et biophysica Sinica Vol. 44; no. 11; pp. 897 - 901
Main Authors Xie, Qi, Chen, Jing, Yuan, Zengqiang
Format Journal Article
LanguageEnglish
Published China 01.11.2012
Subjects
Acetylation
Forkhead Transcription Factors - metabolism
Glycosylation
Humans
Methylation
Phosphorylation
Protein Processing, Post-Translational
Ubiquitination
家族
应激性
生物学功能
细胞周期
细胞死亡
翻译后修饰
调控
转录因子
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Summary:The Forkhead box O （FOXO） family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post- translational modifications, which are closely related to their activity. In this paper, we review the post-translational modifications of FOXOs and their biological functions.
Bibliography:31-1940/Q
The Forkhead box O （FOXO） family transcription factors play critical roles in a series of cellular processes, including the cell cycle, cell death, metabolism, and oxidative stress resistance. FOXO proteins are subject to several post- translational modifications, which are closely related to their activity. In this paper, we review the post-translational modifications of FOXOs and their biological functions.
FOXO; phosphorylation; acetylation; ubiquiti-nation; methylation
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ISSN:1672-9145
1745-7270
1745-7270
DOI:10.1093/abbs/gms067