Pediatric Migraine Headache — Still Searching for Effective Treatments

Migraine headaches are common in children, adolescents, and adults. In children, migraines have a considerable effect on development, often leading to missed school days, educational delays, and decreased socialization. 1 In adults, migraine headaches result in a considerable number of days lost fro...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 376; no. 2; pp. 169 - 170
Main Author Jackson, Jeffrey L
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 12.01.2017
Subjects
Adolescents
Antidepressants
Child
Children
Children & youth
Clinical trials
Drug therapy
Headache
Humans
Migraine
Migraine Disorders
Pediatrics
Pharmaceuticals
Placebo effect
Treatment Outcome
Tricyclic antidepressants
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Summary:Migraine headaches are common in children, adolescents, and adults. In children, migraines have a considerable effect on development, often leading to missed school days, educational delays, and decreased socialization. 1 In adults, migraine headaches result in a considerable number of days lost from work. Although there have been hundreds of randomized clinical trials evaluating prophylactic treatment of migraine headache in adults, there have been few controlled studies involving children. In adults, tricyclic antidepressants have shown the greatest benefit in reducing the incidence of migraine headache, but the reduction is modest (a relative difference of approximately 30% as compared with placebo), leaving . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Editorial-2
ObjectType-Commentary-1
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMe1614628