Reflections on the Applications of Immunohistochemistry to Understanding the Maintenance of Electrochemical Gradients in the Inner Ear

The author of the accompanying classic paper from the Journal of Histochemistry and Cytochemistry (Crouch JJ, Sakaguchi N, Lytle C, Schulte BA. Immunohistochemical localization of the Na-K-Cl Co-transporter (NKCC1) in the Gerbil Inner Ear. Journal of Histochemistry & Cytochemistry 1997;45(6):773...

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Bibliographic Details
Published inThe journal of histochemistry and cytochemistry Vol. 71; no. 9; pp. 509 - 510
Main Author Schulte, Bradley A.
Format Journal Article
LanguageEnglish
Published Los Angeles, CA SAGE Publications 01.09.2023
Subjects
endocochlear potential (EP)
mammalian cochlea
vestibular system
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Summary:The author of the accompanying classic paper from the Journal of Histochemistry and Cytochemistry (Crouch JJ, Sakaguchi N, Lytle C, Schulte BA. Immunohistochemical localization of the Na-K-Cl Co-transporter (NKCC1) in the Gerbil Inner Ear. Journal of Histochemistry & Cytochemistry 1997;45(6):773-778) comments on how the immunohistochemical techniques used in the study provided critical new information that helped define the cellular and molecular mechanisms involved in the generation and maintenance of electrochemical gradients in the ear, particularly the presence of the Na,K,2Cl symporter (NKCC) in the inner ear. (J Histochem Cytochem 71: 509–510, 2023)
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content type line 23
ISSN:0022-1554
1551-5044
1551-5044
DOI:10.1369/00221554231190438