Aspergillus Infections

To the Editor: We would like to make two observations regarding the review of aspergillus infections by Thompson and Young (Oct. 14 issue). 1 The first is the importance of combined diagnostic assays. In most centers, the diagnosis of invasive aspergillosis relies on a single mycologic test — typica...

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Bibliographic Details
Published inThe New England journal of medicine Vol. 386; no. 2; pp. 198 - 199
Main Authors Ceesay, M. Mansour, Mehra, Varun, Pagliuca, Antonio, Thompson III, George R, Young, Jo-Anne H
Format Journal Article
LanguageEnglish
Published United States Massachusetts Medical Society 13.01.2022
Subjects
Aspergillosis
Aspergillosis - diagnosis
Conflicts of interest
Humans
Infections
Leukemia
Patients
Polymerase chain reaction
Tomography
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Summary:To the Editor: We would like to make two observations regarding the review of aspergillus infections by Thompson and Young (Oct. 14 issue). 1 The first is the importance of combined diagnostic assays. In most centers, the diagnosis of invasive aspergillosis relies on a single mycologic test — typically, the galactomannan assay, which is often performed once or twice a week. Galactomannan is released intermittently during infection, but the dynamics of its release are unclear. 2 The authors cited evidence suggesting that combining the use of galactomannan with a polymerase-chain-reaction assay improves diagnostic accuracy. However, some evidence suggests that the combination of . . .
Bibliography:SourceType-Other Sources-1
content type line 63
ObjectType-Correspondence-1
ObjectType-Commentary-2
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc2117819