Screening and GC-MS profiling of ethanolic extract of Tylophora pauciflora

• Published in: Bioinformation Vol. 15; no. 6; pp. 425 - 429
• Main Authors: Starlin, Thangarajan, Prabha, Poochi Saravana, Thayakumar, Basanth Kumar Allen, Gopalakrishnan, Velliyur Kanniappan
• Format: Journal Article
• Language: English
• Published: Singapore Biomedical Informatics 2019
• Subjects: Anti-inflammatory agents; Antifibrinolytic agents; Antimicrobial activity; Antioxidants; Bioactive compounds; Biological activity; Chemical compounds; Fibrin; Flavor; Herbal medicine; Inflammation; Medicinal plants; Organic chemistry; Palmitic acid; Pesticides; Pharmacology; Plant extracts; Raw materials; Reductase; Reductases; Tylophora pauciflora; bioactive compounds; ethanolic extract; GC-MS analysis
• ISSN: 0973-2063; 0973-8894; 0973-2063
• DOI: 10.6026/97320630015425

Medicinal plants are boundless source of raw materials for the pharmaceutical. Identification of natural compounds from medicinal plant is helpful in the discovery of novel therapeutic agents. Tylophora pauciflora is a medicinal plant, which possess many biological activities such as antioxidant activity, anti-inflammatory activity and anti cancer activity. There is no GC-MS analysis reported on this plant. Thus, the present study is aimed to identify the present of phyto-chemical compounds from ethanolic extract of Tylophora pauciflora using GC-MS analysis. Results, the extract possess totally 14 bioactive compounds among that natural compound of n-hexadecanoic acid has highest % peak area and it have the variety of biological activities such as; anti-oxidant, 5-alpha-reductase-inhibitor, anti-fibrinolytic, hemolytic, antimicrobial activity, hypo-cholesterolemic, nematicide, pesticide, anti-androgenic flavor and hemolytic. It is concluded that the ethanolic extract of Tylophora pauciflora have biologically active compounds. In future by isolating and identifying, these compounds can be considered to treat the human disorders.