Ultrasound-assisted extraction of natural antioxidants from betel leaves ( Piper betle ): Extraction kinetics and modeling

Present study investigated the extraction kinetics of antioxidants from Piper betle by ultrasound-assisted extraction for three extraction variables: temperature, solute to solvent ratio and ethanol concentration. Based on the results of yield, total phenolic content and antioxidant activity, the op...

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Bibliographic Details
Published inSeparation science and technology Vol. 53; no. 14; pp. 2192 - 2205
Main Authors Ali, Ameena, Lim, Xiao Yien, Chong, Chien Hwa, Mah, Siau Hui, Chua, Bee Lin
Format Journal Article
LanguageEnglish
Published Abingdon Taylor & Francis Ltd 22.09.2018
Subjects
Antioxidants
Ascorbic acid
Butylated hydroxytoluene
Coefficients
Computer simulation
Ethanol
Eugenol
High performance liquid chromatography
HPLC
Kinetics
Liquid chromatography
Modelling
Phenolic compounds
Phenols
Piper betle
Solutes
Ultrasonic imaging
Ultrasound
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Summary:Present study investigated the extraction kinetics of antioxidants from Piper betle by ultrasound-assisted extraction for three extraction variables: temperature, solute to solvent ratio and ethanol concentration. Based on the results of yield, total phenolic content and antioxidant activity, the optimum results were obtained at 50°C, 1:20 g/mL and 80% ethanol, respectively. Statistical coefficients of R2 [greater than or equal to] 0.961 and RMSE [less-than or equal to] 0.508 for two-site kinetic model confirm the use of proposed models for simulation and prediction purpose. Comparison with ascorbic acid and butylated hydroxytoluene solidifies the use of Piper betle as feasible source of natural antioxidants. The presence of hydroxychavicol and eugenol was affirmed by high-performance liquid chromatography assay.
ISSN:0149-6395
1520-5754
DOI:10.1080/01496395.2018.1443137