Beyond Skin Deep: Phospholipid-Based Nanovesicles as Game-Changers in Transdermal Drug Delivery

• Published in: AAPS PharmSciTech Vol. 25; no. 6; p. 184
• Main Authors: Akl, Mohamed A., Eldeen, Muhammad Alaa, Kassem, Abdulsalam M.
• Format: Journal Article
• Language: English
• Published: Cham Springer International Publishing 13.08.2024
• Subjects: Administration, Cutaneous; Animals; Biochemistry; Biomedical and Life Sciences; Biomedicine; Biotechnology; Drug Carriers - chemistry; Drug Delivery Systems - methods; Humans; Liposomes - chemistry; Nanoparticles - chemistry; Pharmacology/Toxicology; Pharmacy; Phospholipids - chemistry; Review Article; Skin - metabolism; Skin Absorption - drug effects; Skin Absorption - physiology; ethanolic liposome; phospholipid based vesicles; elastic-liposome; transdermal drug delivery; ultra-deformable vesicle; invasomes

Transdermal administration techniques have gained popularity due to their advantages over oral and parenteral methods. Noninvasive, self-administered delivery devices improve patient compliance and control drug release. Transdermal delivery devices struggle with the skin's barrier function. Mol...