Comparison of period-3 correlation amplitudes in genomic DNA sequences

Period-3 oscillations in genome composition can be detected through correlation functions. Since these oscillations are closely related to the genetic code structure, we developed methods for quantitative comparison of genomic and exonic oscillation amplitudes and decay. In contrast to genomic corre...

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Bibliographic Details
Published inGenetics and molecular research Vol. 12; no. 4; pp. 4459 - 4467
Main Authors Guerra, J C O, Licinio, P, Andrade, P C P
Format Journal Article
LanguageEnglish
Published Brazil 10.10.2013
Subjects
Algorithms
Animals
Caenorhabditis elegans - genetics
Drosophila melanogaster - genetics
Escherichia coli K12 - genetics
Exons
Genetic Code
Genome, Bacterial
Genome, Fungal
Genome, Helminth
Genome, Human
Genome, Insect
Humans
Models, Genetic
Saccharomyces cerevisiae - genetics
Sequence Analysis, DNA
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Summary:Period-3 oscillations in genome composition can be detected through correlation functions. Since these oscillations are closely related to the genetic code structure, we developed methods for quantitative comparison of genomic and exonic oscillation amplitudes and decay. In contrast to genomic correlations, exonic period-3 oscillation amplitudes are persistent. A model postulating an uncorrelated distribution of exons in the genome has been applied to the analysis of Escherichia coli K12, Saccharomyces cerevisiae, Caenorhabditis elegans, Drosophila melanogaster, and Homo sapiens genomic decay, allowing for a quantitative discussion of genome organization.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
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ISSN:1676-5680
1676-5680
DOI:10.4238/2013.October.10.11