Maskless microfabrication of thermosensitive gels using a microscope and application to a controlled release microchip

Here we show a simple and convenient method to prepare micropatterned gels by the use of a microscope, without large-scale or special-order experimental setup. UV light focused by an objective lens was locally irradiated to a pre-gel solution in a microchannel. This method would be useful for prepar...

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Bibliographic Details
Published inLab on a chip Vol. 6; no. 10; p. 1384
Main Authors Yoshida, Ryo, Omata, Kazuya, Yamaura, Kotaro, Ebata, Masaya, Tanaka, Masahiro, Takai, Madoka
Format Journal Article
LanguageEnglish
Published England 01.10.2006
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Summary:Here we show a simple and convenient method to prepare micropatterned gels by the use of a microscope, without large-scale or special-order experimental setup. UV light focused by an objective lens was locally irradiated to a pre-gel solution in a microchannel. This method would be useful for preparing microgels at target positions in microchips. A controlled drug-release microchip has actually been fabricated by utilizing this local photo-irradiation method, and pulsatile drug release in response to temperature changes was demonstrated.
ISSN:1473-0197
DOI:10.1039/b606620h