Extricating the Association Between the Prognostic Factors of Colorectal Cancer

• Published in: Journal of gastrointestinal cancer Vol. 52; no. 3; pp. 1022 - 1028
• Main Authors: Mohd, Younis, Balasubramanian, Balamuralikrishnan, Meyyazhagan, Arun, Kuchi Bhotla, Haripriya, Shanmugam, Suresh Kumar, Ramesh Kumar, Mithun Kumar, Pappusamy, Manikantan, Alagamuthu, Karthick Kumar, Keshavarao, Sasikala, Arumugam, Vijaya Anand
• Format: Journal Article
• Language: English
• Published: New York Springer US 01.09.2021
• Subjects: Adult; Aged; Cancer Research; Colorectal Neoplasms - blood; Colorectal Neoplasms - epidemiology; Colorectal Neoplasms - pathology; Female; Gastroenterology; Humans; India - epidemiology; Internal Medicine; Lymphatic Metastasis - pathology; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Grading - statistics & numerical data; Neoplasm Staging - statistics & numerical data; Oncology; Original Research; Prognosis; Radiotherapy; Risk Factors; India; Lymph node metastasis; Haematology; Staging; Colorectal cancer
• ISSN: 1941-6628; 1941-6636
• DOI: 10.1007/s12029-020-00535-4

Purpose Colorectal cancer (CRC) is one of the recurring and lethal gastrointestinal tract disease rankings as the primary cause of worldwide morbidity and mortality. In general, the tumour node metastasis (TNM) and Dukes classification assist in diagnosis, prognosis and treatments of CRC along with haematological examinations and tumour demographic characterisations in patients. Methods The present investigation is carried out on clinically acknowledged sixty-five CRC patients based on haematological findings and are sorted into stages using TNM and Dukes. The present study is to find the association between haematological findings, demographic characters, differentiation position, lymph node invasion and tumour node metastasis in CRC patients in accordance with their age. Results We observed significant ( p < 0.05) nexus between lymph node metastasis and tumour node metastasis on the basis of tumour’s differentiation demographic positioning and age of the individuals. Conclusion Earlier location tracing and medicinal treatment or surgery lessen the chance of CRC morbidity and mortality along with prolonging survival rate via prognostic factors and disease position determination.