A comparative study of Caesalpinia bonduc (L.) Roxb. root extracts on sexual behaviour in male Wistar rats

Caesalpinia bonduc is among the traditionally used plant in Benin, for its enhancement of male sexual activity. This study was undertaken to investigate the potential effect of C. bonduc root extracts on sexual behaviour of male Wistar rats. For that, thirty-six rats were allocated into six groups a...

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Bibliographic Details
Published inAndrologia Vol. 53; no. 7; p. e14072
Main Authors Sindete, Mariette, Rharass, Tareck, Gbankoto, Adam, Yemoa, Achille, Ganfon, Habib, Adjagba, Marius, Ribou, Anne-Cécile
Format Journal Article
LanguageEnglish
Published Germany Wiley Subscription Services, Inc 01.08.2021
Wiley
Subjects
Acetic acid
Analytical chemistry
Body weight
Caesalpinia bonduc
Cancer
Cellular Biology
Chemical Sciences
Citric acid
Dimethyl sulfoxide
Ethanol
Ethyl acetate
Histology
Latency
Life Sciences
or physical chemistry
Reproductive organs
Rodents
Sexual behavior
Sildenafil
Subcellular Processes
Testosterone
Theoretical and
Caesalpinia bonduc
histology
testosterone
sexual behaviour
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Summary:Caesalpinia bonduc is among the traditionally used plant in Benin, for its enhancement of male sexual activity. This study was undertaken to investigate the potential effect of C. bonduc root extracts on sexual behaviour of male Wistar rats. For that, thirty-six rats were allocated into six groups and orally treated with dimethyl sulfoxide (control), Sildenafil citrate (standard) and C. bonduc root extracts (hexane, ethyl acetate, ethanol and methanol) orally for twenty-eight days. Sexual behaviour parameters such as intromission frequency, intromission latency, mount latency and mount frequency were evaluated on day 0, 14 and 28. After the study completion, the body and reproductive organ weights as well as testicular histology and testosterone level were recorded. C. bonduc root extracts treatments had no significant effect on the body weight of rats. Enhancement in sexual behaviour was observed in ethanolic extract treated rats. An significant increase in mount frequency and intromission frequency as well as significant reduction in mount latency and intromission latency were noticed for ethanolic extract. The same extract caused an improvement in testosterone levels, relative testes weight and histological architecture. The findings demonstrate the aphrodisiac potential of C. bonduc root and lend support to the folkloric use as aphrodisiac.
ISSN:0303-4569
1439-0272
DOI:10.1111/and.14072