Series of highly stable Cd()-based MOFs as sensitive and selective sensors for detection of nitrofuran antibiotic

• Published in: CrystEngComm Vol. 23; no. 46; pp. 843 - 852
• Main Authors: Zhou, Shanhe, Lu, Lu, Liu, Dong, Wang, Jun, Sakiyama, Hiroshi, Muddassir, Mohd, Nezamzadeh-Ejhieh, Alireza, Liu, Jianqiang
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 29.11.2021
• Subjects: Antibiotics; Benzene; Carbazoles; Ecological effects; Fluorescence; Hydrogen bonding; Imidazole; Lewis base; Metal-organic frameworks; Topology
• ISSN: 1466-8033; 1466-8033
• DOI: 10.1039/d1ce01264a

The abuse of antibiotics has caused global problems including critical environmental ecology impacts. Herein, four new metal-organic frameworks (MOFs) - {[Cd(HL)(bic)(H 2 O)]·2H 2 O}( 1 ), {[Cd 3 (L) 2 (bbi) 2 (H 2 O) 2 ]·2H 2 O}( 2 ), [Cd 3 (L) 2 (bib) 2 (H 2 O) 2 ] ( 3 ) and [Cd 3 (L) 2 (idy) 2 ] ( 4 ), where bic = 3,6-bis(imidazol-1-yl)-9 H -carbazole, bbi = 1,1′-(1,4-butanediyl)bis(imidazole), bib =1,4-bis(1-imidazoly)benzene and idy = 2-imidazol-1-ylpyridine - have been synthesized and fully characterized. 1 is a 1D chain with a large loop, stacked parallel to each other in 2D supramolecular layers by hydrogen-bonded and packing interactions. 2 and 3 are isostructural and show a 3D (3,8)-connected tfz -type network with (4 3 ) 2 (4 6 ·6 18 ·8 4 ) topology. 4 has a 2D grid framework. The oxygen atom of the ether-bridging group acts as a Lewis base site, which improves the connection strength and allows the detection of 11 types of antibiotics through the fluorescence quenching effect. Among them, 2 exhibits sensitive and selective detection for nitrofural (NZF) ( K SV = 8.26 × 10 3 M −1 and LOD = 1.83 ppm). Moreover, the highly selective probe behavior towards NZF ions could be maintained even if there are other interfering antibiotics. The oxygen atom of the MOF ether-bridging group acts as a Lewis base site, improving the connection and allowing the detection of 10 antibiotics through the fluorescence quenching effect.