New nitinol endovascular stent-graft system for abdominal aortic aneurysm with finite element analysis and experimental verification

Abdominal aortic aneurysm (AAA) is one of the most common and catastrophic manifestations of the acute aortic syndrome that can be treated with endovascular aneurysm repair (EVAR) which requires a specially designed stent-graft system. In this work, a self-expanding nickel–titanium (nitinol) stent-g...

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Published inRare metals Vol. 38; no. 6; pp. 495 - 502
Main Authors Zhou, Xiao-Chen, Yang, Fan, Gong, Xiao-Yan, Zhao, Ming, Zheng, Yu-Feng, Sun, Zhi-Li
Format Journal Article
LanguageEnglish
Published Beijing Nonferrous Metals Society of China 04.06.2019
Springer Nature B.V
Subjects
Aneurysms
Biomaterials
Chemistry and Materials Science
Clinical trials
Energy
Finite element analysis
Finite element method
Grafting
Intermetallic compounds
Materials Engineering
Materials Science
Mathematical analysis
Medical research
Metallic Materials
Nanoscale Science and Technology
Nickel titanides
Physical Chemistry
Shape memory alloys
Stents
Surgical implants
Titanium base alloys
Stent-graft system
Fatigue safety factor
Radial force
Finite element analysis
Nitinol
Abdominal aortic aneurysm
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Summary:Abdominal aortic aneurysm (AAA) is one of the most common and catastrophic manifestations of the acute aortic syndrome that can be treated with endovascular aneurysm repair (EVAR) which requires a specially designed stent-graft system. In this work, a self-expanding nickel–titanium (nitinol) stent-graft system is aiming at AAA using finite element analysis (FEA) methods to analyze both fatigue behaviors and radial forces. Based on the systematic analysis of the parametric variations, a final stent-graft system was developed by the selection and arrangement of the individual stent components, targeting an optimal performance for the treatment of AAA. Experimental tests, animal tests and clinical trials were carried out to confirm the results. Both animal trials and clinical trials showed comparable curative effects with Medtronic Endurant stent-graft (SG) systems.
ISSN:1001-0521
1867-7185
DOI:10.1007/s12598-019-01250-1