The Effect of Exposure to Simulated Body Fluids on Breakdown Potentials

Current methods to evaluate the corrosion resistance of small medical implants are typically based on short-term in vitro tests. While the duration of these tests is kept to a minimum to make it feasible to evaluate a large number of samples in a reasonable time, these methods do not account for the...

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Bibliographic Details
Published inJournal of materials engineering and performance Vol. 18; no. 5-6; pp. 754 - 759
Main Author Warner, Clifford P.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.08.2009
Springer Nature B.V
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Summary:Current methods to evaluate the corrosion resistance of small medical implants are typically based on short-term in vitro tests. While the duration of these tests is kept to a minimum to make it feasible to evaluate a large number of samples in a reasonable time, these methods do not account for the long-term changes that can occur in the oxides of metals exposed to biological fluids. Given other electrochemical changes to these materials with time in solution, it is a reasonable question to consider whether breakdown potentials are a fundamental parameter of a material and surface condition. Data on 316L and nitinol wire samples, and nitinol stents, show that breakdown potentials increase with time in solution up to 28 days. The difference between the breakdown potential and rest potentials either increased or exhibited no change.
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ISSN:1059-9495
1544-1024
DOI:10.1007/s11665-009-9404-z