Vulvovaginal candidiasis refractory to treatment with fluconazole

• Published in: European journal of obstetrics & gynecology and reproductive biology Vol. 44; no. 1; pp. 77 - 80
• Main Authors: Arilla, M.C., Carbonero, J.L., Schneider, J., Regúlez, P., Quindós, G., Pontón, J., Cisterna, R.
• Format: Journal Article Conference Proceeding
• Language: English
• Published: Shannon Elsevier Ireland Ltd 23.03.1992; Elsevier
• Subjects: Adult; Antibiotics. Antiinfectious agents. Antiparasitic agents; Antifungal agents; Biological and medical sciences; Candidiasis; Candidiasis, Vulvovaginal - complications; Candidiasis, Vulvovaginal - drug therapy; Drug Resistance, Microbial; Female; Fertilization in Vitro; Fluconazole; Fluconazole - therapeutic use; Humans; Infertility, Female - complications; Infertility, Female - therapy; Medical sciences; Pharmacology. Drug treatments; Pregnancy; Vagina; Vulva; Vagina; Candidiasis; Vulva; Fluconazole; Fungi; Infection; Human; Vulvovaginitis; Mycosis; Candida glabrata; Fungi Imperfecti; Negative therapeutic reaction; Female genital diseases; Thallophyta
• ISSN: 0301-2115; 1872-7654
• DOI: 10.1016/0028-2243(92)90317-R

We present the case of an infertile patient, whose first attempt at IVF had to be postponed for 18 months due to a vulvovaginal yeast infection refractory to treatment. The main causative organism was a Candida glabrata strain resistant to all the imidazolic agents tested. The organism and the host's humoral status were studied in depth, looking for possible causes of the refractoriness to treatment.