Improvement in left ventricular dysfunction after surgical correction of mitral regurgitation

• Published in: Arquivos brasileiros de cardiologia Vol. 80; no. 1; pp. 13 - 18
• Main Authors: da Rocha, Antônio Sérgio Cordeiro, da Rocha, Nazareth de Novaes, Soares, Rita de Cássia Villela, Coimbra, Marialda, Ramos, Rosana Grandelle, Weksler, Clara, Cruz Filho, Fernando Eugênio, da Silveira, Celso Garcia, da Silva, Paulo Roberto Dutra
• Format: Journal Article
• Language: English
• Published: Brazil Sociedade Brasileira de Cardiologia - SBC 01.01.2003; Sociedade Brasileira de Cardiologia (SBC)
• Subjects: Adolescent; Adult; Analysis of Variance; CARDIAC & CARDIOVASCULAR SYSTEMS; Chronic Disease; cirurgia valvar mitral; Diastole; disfunção ventricular esquerda; Female; Humans; Male; Middle Aged; Mitral Valve Insufficiency - surgery; Postoperative Period; Preoperative Care; regurgitação mitral; Systole; Time Factors; tratamento cirúrgico; Treatment Outcome; Ventricular Dysfunction, Left - surgery; cirurgia valvar mitral; mitral valvar correction; regurgitação mitral; mitral regurgitation; tratamento cirúrgico; disfunção ventricular esquerda; left ventricular dysfunction; surgical correction
• ISSN: 0066-782X; 1678-4170; 0066-782X
• DOI: 10.1590/S0066-782X2003000100002

To evaluate whether left ventricular end-systolic (ESD) diameters < or = 51mm in patients (pt) with severe chronic mitral regurgitation (MR) are predictors of a poor prognosis after mitral valve surgery (MVS). Eleven pt (aged 36 +/- 13 years) were studied in the preoperative period (pre), median of 36 days; in the early postoperative period (post1), median of 9 days; and in the late postoperative period (post2), mean of 38.5 +/- 37.6 months. Clinical and echocardiographic data were gathered from each pt with MR and systolic diameter > or = 51 mm (mean = 57 +/- 4mm) to evaluate the result of MVS. Ten patients were in NYHA Class III/IV. All but 2 pt improved in functional class. Two pt died from heart failure and infectious endocarditis 14 and 11 months, respectively, after valve replacement. According to ejection fraction (EF) in post2, we identified 2 groups: group 1 (n=6), whose EF decreased in post1, but increased in post2 (p=0.01) and group 2 (n=5), whose EF decreased progressively from post1 to post2 (p=0.10). All pt with symptoms lasting < or = 48 months had improvement in EF in post2 (p=0.01). ESD > or = 51 mm are not always associated with a poor prognosis after MVS in patients with MR. Symptoms lasting up to 48 months are associated with improvement in left ventricular function.