SCAR DNA family is enriched in evolutionarily conserved sequences

The family of DNA sequences tightly associated with the synaptonemal complex (SC), or SCAR DNA family, has earlier been described as a specific family of golden hamster genomic DNA sequences. DNA sequences similar to golden hamster SCAR DNA proved to be widespread in the genomes of some vertebrates....

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Published inMolecular biology (New York) Vol. 42; no. 2; pp. 321 - 327
Main Authors Penkina, M. V., Karpova, O. I., Zakharevich, N. V., Sizova, T. V., Bogdanov, Yu. F.
Format Journal Article
LanguageEnglish
Published Dordrecht SP MAIK Nauka/Interperiodica 01.04.2008
Springer Nature B.V
Subjects
Biochemistry
Biomedical and Life Sciences
Cell cycle
Cell division
Deoxyribonucleic acid
DNA
Genomics
Human Genetics
Life Sciences
Mathematical and Systems Biology
Molecular biology
SCAR DNA
meiosis
synaptonemal complex
evolutionary conservation
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Summary:The family of DNA sequences tightly associated with the synaptonemal complex (SC), or SCAR DNA family, has earlier been described as a specific family of golden hamster genomic DNA sequences. DNA sequences similar to golden hamster SCAR DNA proved to be widespread in the genomes of some vertebrates. A comparison with a sample of random sequences showed that the SCAR DNA family is enriched in evolutionarily conserved sequences, which correlates with the universal SC morphology and processes occurring in meiotic prophase I.
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ISSN:0026-8933
1608-3245
DOI:10.1134/S0026893308020192