Superoxide-Mediated Regioselective Deblocking of the Tosyl Group from N-Tosylcarboxamides

In situ-generated tetraethylammonium superoxide brings about an easy and selective cleavage of the N‒S bond of N-tosylcarboxamides, providing a new method for the deblocking of the tosyl group from such substrates.

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Bibliographic Details
Published inSynthetic communications Vol. 36; no. 20; pp. 3075 - 3078
Main Authors Raghuvanshi, R. S., Singh, K. N.
Format Journal Article
LanguageEnglish
Published PHILADELPHIA Taylor & Francis Group 01.10.2006
Taylor & Francis
Subjects
Chemistry
Chemistry, Organic
Detosylation
N-tosylcarboximide
Physical Sciences
Science & Technology
superoxide
N-tosylcarboximide
DEPROTECTION
superoxide
DESULFONYLATION
detosylation
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Summary:In situ-generated tetraethylammonium superoxide brings about an easy and selective cleavage of the N‒S bond of N-tosylcarboxamides, providing a new method for the deblocking of the tosyl group from such substrates.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397910600775416