Dichloro[N-[(η6-phenyl)methyl]-4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8tetrahydronaphthalen-2-yl)vinyl)benzamide](1,3,5-triaza-7-phosphatricyclo [3.3.1.13,7]decane-κP7)ruthenium

Bexarotene-tethered RuII(arene) compounds with 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (PTA) were prepared as an analog of RAPTA antitumor complexes in order to evaluate their in vitro antiproliferative activity against human cancer cell lines.

Saved in:
Bibliographic Details
Published inMolBank Vol. 2022; no. 4; p. M1506
Main Authors Shutkov, Ilya A., Mazur, Dmitrii M., Borisova, Nataliya E., Milaeva, Elena R., Nazarov, Alexey A.
Format Journal Article
LanguageEnglish
Published Basel MDPI AG 01.12.2022
Subjects
antiproliferative activity
Benzamide
bexarotene
Conflicts of interest
FDA approval
Gastric cancer
Investigations
Ligands
PTA ligand
Ruthenium
ruthenium compounds
United Kingdom > UK
Online AccessGet full text

Cover

More Information
Summary:Bexarotene-tethered RuII(arene) compounds with 1,3,5-triaza-7-phosphatricyclo[3.3.1.1]decane (PTA) were prepared as an analog of RAPTA antitumor complexes in order to evaluate their in vitro antiproliferative activity against human cancer cell lines.
ISSN:1422-8599
1422-8599
DOI:10.3390/M1506