Small Silencing RNAs: Piecing Together a Viral Genome

Virus-derived small interfering RNAs (siRNAs) are the hallmark of RNAi-based antiviral immunity. Wu and colleagues demonstrate how viral genomes can be assembled from these small RNA sequences. Their results provide an approach for virus discovery as well as important insights into how these siRNAs...

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Bibliographic Details
Published inCell host & microbe Vol. 7; no. 2; pp. 87 - 89
Main Authors van Mierlo, Joël T, van Cleef, Koen W R, van Rij, Ronald P
Format Journal Article
LanguageEnglish
Published United States 18.02.2010
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Summary:Virus-derived small interfering RNAs (siRNAs) are the hallmark of RNAi-based antiviral immunity. Wu and colleagues demonstrate how viral genomes can be assembled from these small RNA sequences. Their results provide an approach for virus discovery as well as important insights into how these siRNAs mediate antiviral defense.
Bibliography:ObjectType-Article-2
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ISSN:1931-3128
1934-6069
DOI:10.1016/j.chom.2010.02.001