Association of Rs7217186 Polymorphism of Arachidonic Acid 15-Lipoxygenase (ALOX15) Gene with Susceptibility to Allergic Rhinitis

• Published in: Reports of biochemistry and molecular biology Vol. 12; no. 2; pp. 269 - 276
• Main Authors: Eivazi, Atefeh, Akbari, Bahman, Falahi, Sara, Gorgin Karaji, Ali, Rezaiemanesh, Alireza, Mortazavi, Seyed Hamid Reza, Daneshfar, Niloofar, Salari, Farhad
• Format: Journal Article
• Language: English
• Published: Iran Varastegan Institute for Medical Sciences 01.07.2023
• Subjects: Original; Specialized proresolving lipid mediators (SPMs); Immunoresolvents; Single-nucleotide polymorphism; Allergic rhinitis; Arachidonate 15-lipoxygenase

Allergic rhinitis (AR) is an inflammatory disorder of the nasal mucosa, caused by exposure to environmental allergens. It is known that 15-lipoxygenase (15-LOX) is involved in the biosynthetic pathways of anti-inflammatory lipid mediators, including resolvins and protectins. In this study, which was...