Synthesis of Phosphonium Salts-Phosphine Structure and Inorganic Salts Effects
Solvent-free reactions of 2- and 3-halopyridines with PPh 3 , PBu 3 , and PCy 3 were studied under conventional heating, as well as under microwave irradiation. No difference was observed in the reaction course between classical and microwave reactions. 2-Bromopyridine gave quantitative yields of 2-...
Saved in:
Published in | Phosphorus, sulfur, and silicon and the related elements Vol. 183; no. 1; pp. 21 - 33 |
---|---|
Main Authors | , , , |
Format | Journal Article |
Language | English |
Published |
ABINGDON
Taylor & Francis Group
01.01.2008
Taylor & Francis |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Solvent-free reactions of 2- and 3-halopyridines with PPh
3
, PBu
3
, and PCy
3
were studied under conventional heating, as well as under microwave irradiation. No difference was observed in the reaction course between classical and microwave reactions. 2-Bromopyridine gave quantitative yields of 2-pyridyltriphenylphosphonium bromide within few minutes at 190°C. Equimolar amounts of some inorganic salts (LiPF
6
, LiOTf, LiBr, NaPF
6
, KPF
6
) were necessary for the reactions of the other 2-halopyridines. 3-Halopyridines did not react with PPh
3
even in the presence of LiPF
6
. Their reactions with PCy
3
in the presence of LiPF
6
resulted in the quantitative formation of dicyclohexylphosphine oxide. |
---|---|
ISSN: | 1042-6507 1563-5325 |
DOI: | 10.1080/10426500701545950 |