Genetic diversities of 23 Y-Chromosome short tandem repeat loci in a han population in the Beijing Region

• Published in: Journal of forensic science and medicine Vol. 4; no. 2; pp. 111 - 114
• Main Authors: Hao, Shicheng, Zhang, Xuan, Liu, Yan, Lu, Di
• Format: Journal Article
• Language: English
• Published: Mumbai Medknow Publications and Media Pvt. Ltd 01.04.2018; Medknow Publications & Media Pvt. Ltd; Wolters Kluwer Medknow Publications
• Subjects: Backup software; Binding sites; Biodiversity; Chromosomes; Civilization; Collaboration; Deoxyribonucleic acid; Discrimination; DNA; Education; Forensic biology; Genes; Genetic aspects; genetic polymorphism; Haplotypes; Identification; Laboratories; Males; Multiculturalism & pluralism; Political science; Population; Statistical analysis; Y-short tandem repeat; Beijing China; New York; United States > US; China
• ISSN: 2349-5014; 2455-0094
• DOI: 10.4103/jfsm.jfsm_12_18

We investigated the polymorphisms of 23 Y-short tandem repeat (STR) loci in a Han population in the Beijing region. Blood samples were collected from 255 unrelated Han males. DNA templates were amplified using the PowerPlex® Y23 system, and the amplification products were detected with a 3130 genetic analyzer. A total of 254 haplotypes were detected from the 255 unrelated Han males in the Beijing region. The gene diversity of these 23 Y-STR loci was 0.3952-0.9721. The haplotype diversity was 0.99996 and discrimination capacity (DC) was more than 99.6%. The 23 Y-STR loci used in this study are highly polymorphic in Han individuals in the Beijing region and are therefore suitable for paternal kinship identification. Studying allelic deletions such as DYS448 and DYS549 are important for examining Y-STR polymorphisms and forensic testing.