Calcitonin treatment in osteoectasia with hyperphosphatasia (juvenile Paget's disease): radiographic changes after treatment

• Published in: Pediatric radiology Vol. 29; no. 11; pp. 838 - 841
• Main Authors: TÜYSÜZ, B, MERCIMEK, S, ÜNGÜR, S, DENIZ, M
• Format: Journal Article
• Language: English
• Published: Berlin Springer 01.11.1999; Springer Nature B.V
• Subjects: Acid Phosphatase - blood; Alkaline Phosphatase - blood; Biological and medical sciences; Bone and Bones - diagnostic imaging; Calcitonin - therapeutic use; Female; Hormones. Endocrine system; Humans; Infant; Medical sciences; Osteitis Deformans - diagnostic imaging; Osteitis Deformans - drug therapy; Pharmacology. Drug treatments; Radiography; Human; Paget disease of bone; Radiodiagnosis; Treatment efficiency; Peptide hormone; Diseases of the osteoarticular system; Metabolic diseases; Infant; Bone disease; Neuropeptide; Inorganic element; Genetic disease; Case study; Radiography; Chemotherapy; Hyperphosphatasia; Surveillance; Calcitonin; Thyroid hormone; Female; Osteochondrodysplasia
• ISSN: 0301-0449; 1432-1998
• DOI: 10.1007/s002470050708

Osteoectasia with hyperphosphatasia is a rare skeletal disorder, characterised by demineralisation and expansion of tubular bones and elevated serum alkaline phosphatase. We present a girl diagnosed as having osteoectasia with hyperphosphatasia who had swelling of phalanges of both hands and motor retardation. She was treated with synthetic human calcitonin. Clinical and radiological findings showed remarkable improvement after 2 years' treatment.