Identification of new genovariants of canine distemper virus in dogs from the State of Mexico by analyzing the nucleocapsid gene

Globally, Canine Distemper Disease is one of the most important viral diseases in dogs due to its high mortality and morbidity. It is caused by an RNA canine paramyxovirus with an elevated genetic diversity. We previously reported the presence of an apparently exclusive genovariant in the State of M...

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Bibliographic Details
Published inArchivos de medicina veterinaria Vol. 44; no. 1; pp. 53 - 58
Main Authors Gámiz-Mejía, CE, Simón-Martínez, J, Fajardo-Muñoz, RC
Format Journal Article
LanguageEnglish
Published Facultad de Ciencias Veterinarias, Universidad Austral de Chile 2012
Subjects
VETERINARY SCIENCES
diversidad genética
genetic diversity
gen N
canine distemper virus
N gen
virus del distemper canino
nuevas genovariantes virales
new viral genovariants
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Summary:Globally, Canine Distemper Disease is one of the most important viral diseases in dogs due to its high mortality and morbidity. It is caused by an RNA canine paramyxovirus with an elevated genetic diversity. We previously reported the presence of an apparently exclusive genovariant in the State of Mexico, but we do not have data on molecular epidemiology of this virus. In order to determine his genetic diversity in this State, samples collected from dogs showing clinical signs of Distemper Disease were analyzed. The samples were processed by RT-PCR and the nucleotide sequence of an N gene fragment was obtained. The data analysis was performed using molecular phylogeny. The results showed that N gene sequences belong to seven Canine Distemper Virus genovariants that had never been reported before in the State of Mexico.
ISSN:0301-732X
DOI:10.4067/S0301-732X2012000100008