Ring melanoma of the ciliary body: clinical and ultrasound biomicroscopic characteristics

Abstract Background: Diagnosis of ring melanoma is clinically difficult since the mass can remain hidden with standard slit-lamp biomicroscopy. The aim of this study was to evaluate the utility of ultrasound biomicroscopy (UBM) as a diagnostic tool for ring melanoma of the ciliary body. Methods: Thi...

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Published inCanadian journal of ophthalmology Vol. 43; no. 2; pp. 229 - 233
Main Authors Vásquez, Luz M., MD, Pavlin, Charles J., MD, FRCSC, McGowan, Hugh, MD, FRCSC, Simpson, E. Rand, MD, FRCSC
Format Journal Article
LanguageEnglish
Published England Elsevier Inc 01.04.2008
Subjects
Adult
Aged
Ciliary Body - diagnostic imaging
Ciliary Body - pathology
Female
Gonioscopy
heterochromy
Humans
Internal Medicine
Male
Melanoma - diagnostic imaging
Melanoma - pathology
Microscopy, Acoustic
Middle Aged
Ophthalmology
Retrospective Studies
ultrasonography
uveal neoplasms
Uveal Neoplasms - diagnostic imaging
Uveal Neoplasms - pathology
heterochromy
ultrasonography
uveal neoplasms
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Summary:Abstract Background: Diagnosis of ring melanoma is clinically difficult since the mass can remain hidden with standard slit-lamp biomicroscopy. The aim of this study was to evaluate the utility of ultrasound biomicroscopy (UBM) as a diagnostic tool for ring melanoma of the ciliary body. Methods: This was a retrospective study of 6 eyes of 6 patients at Princess Margaret Hospital,Toronto, Ont., with a diagnosis of ring melanoma of the ciliary body. The tumor extension was measured clinically, gonioscopically, ultrasonographically (by UBM), and pathologically. Results: Since 2000, 6 cases of ring melanoma have been diagnosed at Princess Margaret Hospital: 2 women and 4 men, median age 57 years. Five patients presented as uncontrolled hyperchromic glaucoma (83%). Ciliary body involvement on slit-lamp examination ranged from 60° to 180°. Ciliary body involvement as assessed by UBM ranged from 180° to 300°. Tumor extension according to pathological examination ranged from 210° to 360°. With these measures, the ring melanoma clinical criteria were not filled by 5 patients. Interpretation: UBM is an important tool in determining the extent of ciliary body involvement and classifying these lesions.
ISSN:0008-4182
1715-3360
DOI:10.3129/i08-025