Combined treatment of immune nephropathies with plasmapheresis and immunosuppressants

The treatment of patients with immune nephropthies is discussed: rapidly progressive nephritis, lupus nephropathy, Wegener granulomatosis, Goodpasture syndrome, Schonlein-Henoch nephritis. A combined treatment of plasmapheresis and immunosuppressants is applied. A definite result, specially with the...

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Bibliographic Details
Published inBiomaterials, artificial cells, and artificial organs Vol. 16; no. 5; p. 991
Main Authors Nenov, D, Metodiev, K
Format Journal Article
LanguageEnglish
Published United States 1988
Subjects
Adolescent
Adult
Animals
Antigen-Antibody Complex - metabolism
Combined Modality Therapy
Female
Humans
Immunoglobulin A - metabolism
Immunoglobulin G - metabolism
Immunosuppressive Agents - therapeutic use
Kidney Diseases - immunology
Kidney Diseases - therapy
Male
Paramecium - immunology
Plasmapheresis
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Summary:The treatment of patients with immune nephropthies is discussed: rapidly progressive nephritis, lupus nephropathy, Wegener granulomatosis, Goodpasture syndrome, Schonlein-Henoch nephritis. A combined treatment of plasmapheresis and immunosuppressants is applied. A definite result, specially with the cases of Wegener granulomatosis, is registered for certain number of the patients. Together with the usual tests: CIC, immunoglobulins, complement, etc. a method for controlling of the detoxic efficiency of the treatment is suggested. This is a biologic method- the level of paramecium caudatum in media from patients' plasma is registered in relation to time. After plasmapheresis the life of paramecium caudatum is considerably prolonged.
ISSN:0890-5533
DOI:10.3109/10731198809117284