Intraoperative Doppler ultrasound in liver transplantation

• Published in: Clinical transplantation Vol. 12; no. 4; p. 292
• Main Authors: Cheng, Y F, Huang, T L, Chen, C L, Lee, T Y, Chen, T Y, Chen, Y S, Liu, P P, Chiang, Y C, Eng, H L, Wang, C C, Cheung, H K, Jawan, B, Goto, S
• Format: Journal Article
• Language: English
• Published: Denmark 01.08.1998
• Subjects: Adolescent; Adult; Aged; Angioplasty, Balloon; Child; Child, Preschool; Constriction, Pathologic - diagnostic imaging; Embolization, Therapeutic; Female; Graft Survival; Hemodynamics - physiology; Hepatic Artery - diagnostic imaging; Hepatic Veins - diagnostic imaging; Humans; Infant; Intraoperative Complications - diagnostic imaging; Liver Transplantation - adverse effects; Liver Transplantation - diagnostic imaging; Living Donors; Male; Middle Aged; Portal Vein - diagnostic imaging; Pulsatile Flow - physiology; Regional Blood Flow - physiology; Renal Veins - pathology; Reoperation; Reperfusion; Splenic Vein - pathology; Thrombectomy; Thrombosis - diagnostic imaging; Thrombosis - surgery; Ultrasonography, Doppler; Ultrasonography, Interventional; Vascular Fistula - diagnostic imaging; Vascular Fistula - therapy; Vascular Patency - physiology
• ISSN: 0902-0063
• DOI: 10.1111/j.1399-0012.1998.tb00972.x

The purpose of this study was to determine the utility of intraoperative Doppler ultrasound for the diagnosis and reduction of the vascular complications in liver transplantation. This study included 19 pediatric and 5 adult patients. In the pediatric group, 12 patients received living related liver transplantation (LRLT), two splitting liver transplantation (SLT), three reduced-size liver transplantation (RLT) and two full-size pediatric liver transplants (FPLT). The hemodynamics and waveform of the hepatic vein, portal vein and hepatic artery were evaluated by intraoperative Doppler ultrasound (US) after reperfusion of the graft. Unsatisfactory hemodynamics was identified in nine cases, including decrease hepatic venous flow (6-9 cm/s) with non-pulsative flat waveform (adults, n = 2 and LRLT, n = 2); portal vein thrombosis (LRLT, n = 1); decrease portal flow (8 mL/min/kg) (LRLT, n = 1); occlusion of the portal vein (SLT, n = 1); poor arterial flow with dampened artery waveform (FPLT, n = 2). These abnormalities were all successfully re-reconstructed by surgical procedures and achieved a graft survival rate of 100%. Two late vascular complications including hepatic venous thrombosis and recurrent portal vein stenosis with splenorenal shunt were discovered 1 month later. They were treated effectively by surgical thrombolectomy and percutaneous balloon dilatation and metallic coils embolization respectively. Three patients died of non-vascular complications and all patients who underwent LRLT survived with a resultant 87.5% overall survival rate. In conclusion, intraoperative Doppler US is efficient in detecting abnormal hepatic hemodynamics, which permits early intervention and hence a better prognosis for the patients. Re-reconstructive procedures were monitored closely under Doppler US guidance until proper flow and wave-form were established. This reduces post-transplant vascular complications and thereby eliminates the likelihood of a lethal complication that might call for re-transplantation.