Breast Cancer to Meningioma: A Rare Case of Tumor-to-Tumor Metastasis

• Published in: Brain tumor research and treatment Vol. 11; no. 1; pp. 73 - 78
• Main Authors: Joe, Woo Hyeong, Lee, Chang-Young, Kim, Chang-Hyun, Ko, Young San, Kim, Sang Pyo, Kwon, Sae Min
• Format: Journal Article
• Language: English
• Published: Korea (South) The Korean Brain Tumor Society; The Korean Society for Neuro-Oncology; The Korean Society for Pediatric Neuro-Oncology 2023; 대한뇌종양학회
• Subjects: Case Report; 신경외과학; Tumor-to-tumor metastasis; Breast cancer; Meningioma
• ISSN: 2288-2405; 2288-2413
• DOI: 10.14791/btrt.2022.0042

Tumor-to-tumor metastasis (TTM) is defined as the hematogenous metastasis within a primary host tumor from a donor neoplasm. Since there is insufficient evidence regarding the pathophysiology, clinical course, and management of TTM, there are no precise guidelines for its management. A 73-year-old female patient diagnosed with breast cancer was found to have convexity meningioma. Since the size of tumor and peritumoral brain edema increased during follow-up period, the meningioma was treated with surgical resection. Postoperatively, histopathologic examination confirmed metastasis of invasive ductal carcinoma within a secretory meningioma. The final diagnosis was TTM of breast cancer in meningioma. Here, we report a rare case of intra-meningioma metastasis and a review of literature to provide a better understanding of this rare phenomenon.