Hepatic focal nodular hyperplasia after liver transplantation: case report and review of literature
Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whet...
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| Published in | Clinical journal of gastroenterology |
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| Main Authors | , , , , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Japan
18.07.2025
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| Subjects | |
| Online Access | Get full text |
| ISSN | 1865-7257 1865-7265 1865-7265 |
| DOI | 10.1007/s12328-025-02180-5 |
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| Abstract | Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whether it is a recurrence of HCC. Focal nodular hyperplasia (FNH), the second most common benign hepatic tumor, is believed to result from the hyperplastic response of hepatocytes to pre-existing vascular malformation. Here, we report a case of hepatic FNH two years after living-donor liver transplantation in a patient who experienced liver failure following treatment for HCC. Given the rarity of hepatic FNH after liver transplantation, we present this case along with a review of the literature. |
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| AbstractList | Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whether it is a recurrence of HCC. Focal nodular hyperplasia (FNH), the second most common benign hepatic tumor, is believed to result from the hyperplastic response of hepatocytes to pre-existing vascular malformation. Here, we report a case of hepatic FNH two years after living-donor liver transplantation in a patient who experienced liver failure following treatment for HCC. Given the rarity of hepatic FNH after liver transplantation, we present this case along with a review of the literature. Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whether it is a recurrence of HCC. Focal nodular hyperplasia (FNH), the second most common benign hepatic tumor, is believed to result from the hyperplastic response of hepatocytes to pre-existing vascular malformation. Here, we report a case of hepatic FNH two years after living-donor liver transplantation in a patient who experienced liver failure following treatment for HCC. Given the rarity of hepatic FNH after liver transplantation, we present this case along with a review of the literature.Patients with decompensated cirrhosis complicated by hepatocellular carcinoma (HCC) or those who have undergone liver transplantation following liver failure after HCC treatment should continue to receive post-transplant surveillance. Any new liver tumor must be carefully evaluated to determine whether it is a recurrence of HCC. Focal nodular hyperplasia (FNH), the second most common benign hepatic tumor, is believed to result from the hyperplastic response of hepatocytes to pre-existing vascular malformation. Here, we report a case of hepatic FNH two years after living-donor liver transplantation in a patient who experienced liver failure following treatment for HCC. Given the rarity of hepatic FNH after liver transplantation, we present this case along with a review of the literature. |
| Author | Nagata, Kenji Aishima, Shinichi Kawakami, Hiroshi Umekita, Yoshiko Ozono, Yoshinori Hatada, Hiroshi Uchiyama, Naomi Nakamura, Kenichi Komaki, Yuri Iwakiri, Hisayoshi Hasuike, Satoru |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/40679693$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1002/lt.20754 10.1007/s11604-011-0624-4 10.1002/jmri.22262 10.1016/j.jvir.2009.12.385 10.1097/RLI.0b013e3181705cd1 10.2214/ajr.137.5.983 10.1002/jcu.20533 10.1002/hep.1840050622 10.1046/j.1440-1746.2000.2354.x 10.1148/radiol.11101742 10.1097/00000478-199912000-00001 10.1046/j.1440-1746.2001.02576.x 10.1002/lt.21956 10.1097/00000478-197709000-00003 10.1007/s00261-007-9258-5 10.1148/radiol.2291021284 |
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| Keywords | Hepatocellular carcinoma Focal nodular Hyperplasia Liver transplantation |
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