Mass spectrometry for the characterization and quantification of engineered inorganic nanoparticles

•Overview on recent advances of mass spectrometry in nanotechnology.•Use of mass spectrometry for characterization of engineered NPs.•Future trends of MS-based techniques for NPs characterization are discussed. Advancements in nanoscience enabled the synthesis of a diverse array of engineered nanoma...

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Published inTrAC, Trends in analytical chemistry (Regular ed.) Vol. 84; pp. 139 - 148
Main Authors Costa-Fernández, Jose M., Menéndez-Miranda, Mario, Bouzas-Ramos, Diego, Encinar, Jorge Ruiz, Sanz-Medel, Alfredo
Format Journal Article
LanguageEnglish
Published Elsevier B.V 01.11.2016
Subjects
Characterization
Electrospray ionization
Engineered nanoparticles
Field-flow fractionation
Hybrid techniques
ICP-MS
MALDI
Mass spectrometry
Nanoanalysis
Characterization
Nanoanalysis
Engineered nanoparticles
MALDI
Electrospray ionization
Field-flow fractionation
ICP-MS
Mass spectrometry
Hybrid techniques
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Summary:•Overview on recent advances of mass spectrometry in nanotechnology.•Use of mass spectrometry for characterization of engineered NPs.•Future trends of MS-based techniques for NPs characterization are discussed. Advancements in nanoscience enabled the synthesis of a diverse array of engineered nanomaterials. The precise control of the composition and quality of such nanomaterials is required to ensure their eventual successful application. Also importantly, the potentially adverse environmental and/or human health effects resulting from exposure to nanoparticles (NPs) is still a critical but underexplored research area. To understand and assess the potentially harmful effects of NPs a proper knowledge of their physicochemical properties is required. Among the different available analytical tools for the characterization and quantification of engineered inorganic NPs, mass spectrometry (MS) offers outstanding capabilities. The analytical capabilities of different MS-based techniques, including elemental and molecular detection, and hybrid tools derived from their coupling with different separation approaches, to identify, characterize and quantify NPs is here revised. A forward look into trends on the use of MS for more complete chemical analysis of engineered inorganic NPs is finally attempted.
ISSN:0165-9936
1879-3142
DOI:10.1016/j.trac.2016.06.001