Prolonged croup due to herpes simplex virus infection

• Published in: European journal of pediatrics Vol. 157; no. 7; pp. 567 - 569
• Main Authors: KRAUSE, I, SCHONFELD, T, BEN-ARI, J, OFFER, I, GARTY, B. Z
• Format: Journal Article
• Language: English
• Published: Heidelberg Springer 01.07.1998; Berlin Springer Nature B.V
• Subjects: Biological and medical sciences; Croup - virology; Female; Herpes Simplex - complications; Herpes Simplex - diagnosis; Herpesvirus 1, Human - isolation & purification; Human viral diseases; Humans; Infant; Infectious diseases; Medical sciences; Respiratory Sounds; Stomatitis - virology; Viral diseases; Viral diseases of the respiratory system and ent viral diseases; Human; Respiratory disease; Herpesviridae; Acute; Alphaherpesvirinae; Infant; Laryngitis; Infection; Virus; Case study; Herpesvirus hominis 1; Etiology; Viral disease; ENT disease; Larynx disease; Prolonged
• ISSN: 0340-6199; 1432-1076
• DOI: 10.1007/s004310050880

Herpes simplex virus (HSV) is an uncommon cause of acute laryngitis in immunocompetent patients since it mostly occurs in immunocompromised subjects. We present two previously healthy children with prolonged gingivostomatitis and stridor (lasting 3 and 4 weeks) in whom HSV-1 was isolated from subglottal ulcers. HSV should be considered a possible pathogen in cases of prolonged or atypical croup not only in immunocompromised or elderly patients but also in otherwise healthy children.