Recurrent strokes, central nervous system vasculitis, and acquired protein S deficiency secondary to varicella zoster in a child with AIDS

A child with vertical transmission of human immunodeficiency virus refractory to therapy developed zoster-induced protein S deficiency and recurrent strokes. Extensive carotid arteritis was found postmortem. The carotid tissue was positive for herpes varicella zoster by polymerase chain reaction, as...

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Bibliographic Details
Published inJournal of neurovirology Vol. 25; no. 1; pp. 137 - 140
Main Authors Deviley, Jake A., Oldenburg, Darby, Berg, Laurence C., Agger, William A.
Format Journal Article
LanguageEnglish
Published Cham Springer International Publishing 15.02.2019
Subjects
Biomedical and Life Sciences
Biomedicine
Case Report
Immunology
Infectious Diseases
Neurology
Neurosciences
Virology
AIDS
Protein S
Strokes
Zoster
Arteritis
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Summary:A child with vertical transmission of human immunodeficiency virus refractory to therapy developed zoster-induced protein S deficiency and recurrent strokes. Extensive carotid arteritis was found postmortem. The carotid tissue was positive for herpes varicella zoster by polymerase chain reaction, as were immunofixation stains of the arterial wall.
Bibliography:ObjectType-Case Study-2
SourceType-Scholarly Journals-1
ObjectType-Feature-4
content type line 23
ObjectType-Report-1
ObjectType-Article-3
ISSN:1355-0284
1538-2443
DOI:10.1007/s13365-018-0697-2