Derivation of MUSIi016-A iPSCs from peripheral blood with blood type O Rh positive

MUSIi016-A, a human induced pluripotent stem cell (iPSC), generated from peripheral blood mononuclear cells of a healthy blood group O Rh positive donor was reprogrammed using Sendai viral vectors containing Yamanaka’s factors. MUSIi016-A iPSC showed pluripotent stem cell characteristics, highly exp...

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Published inStem cell research Vol. 66; p. 103014
Main Authors Jiamvoraphong, Nittaya, Septham, Prapasri, Klaihmon, Phatchanat, Laowtammathron, Chuti, U-pratya, Yaowalak, Lorthongpanich, Chanchao, Issaragrisil, Surapol
Format Journal Article
LanguageEnglish
Published England Elsevier B.V 01.02.2023
Elsevier
Subjects
Cell Differentiation
Cell Lineage
Humans
Induced Pluripotent Stem Cells
Leukocytes, Mononuclear
Pluripotent Stem Cells
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Summary:MUSIi016-A, a human induced pluripotent stem cell (iPSC), generated from peripheral blood mononuclear cells of a healthy blood group O Rh positive donor was reprogrammed using Sendai viral vectors containing Yamanaka’s factors. MUSIi016-A iPSC showed pluripotent stem cell characteristics, highly expressed pluripotent markers, and a capacity to differentiate into all three embryonic cell lineages. This iPSC can be used as a model for the generation of blood cells in vitro.
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ISSN:1873-5061
1876-7753
DOI:10.1016/j.scr.2022.103014