A Simple Procedure for the Preparation of 4-(α-Mercaptobenzyl)Phenoxyacetic Acid, A Thiol Linker Unit Used in Solid Phase Synthesis of Peptide-α-Thioacids

A convenient procedure for the preparation of the title compound via direct thionation of its alcohol precursor by Lawesson's reagent is described.

Saved in:
Bibliographic Details
Published inSynthetic communications Vol. 27; no. 1; pp. 187 - 194
Main Authors Rajagopalan, Shyamala, Radke, Gary, Tomich, John
Format Journal Article
LanguageEnglish
Published NEW YORK Taylor & Francis Group 01.01.1997
Marcel Dekker Inc
Subjects
Chemistry
Chemistry, Organic
Physical Sciences
Science & Technology
ACTIVATION
REAGENTS
ALPHA-INHIBIN-92
INDOLINE-2-THIONES
LIGATION
PROTEINS
CHEMICAL SYNTHESIS
PROTEASE
AMIDES
Online AccessGet full text

Cover

More Information
Summary:A convenient procedure for the preparation of the title compound via direct thionation of its alcohol precursor by Lawesson's reagent is described.
ISSN:0039-7911
1532-2432
DOI:10.1080/00397919708004820