Hormone-Based Treatments in Subfertile Males

Subfertility is defined as the condition of being less than normally fertile though still capable of effecting fertilization. When these subfertile couples seek assistance for conception, a thorough evaluation of male endocrine function is often overlooked. Spermatogenesis is a complex process where...

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Bibliographic Details
Published inCurrent urology reports Vol. 17; no. 8; p. 56
Main Authors Patel, Darshan P., Chandrapal, Jason C., Hotaling, James M.
Format Journal Article
LanguageEnglish
Published New York Springer US 01.08.2016
Subjects
Adrenal Hyperplasia, Congenital - complications
Adrenal Hyperplasia, Congenital - diagnosis
Androgen-Insensitivity Syndrome - complications
Androgen-Insensitivity Syndrome - diagnosis
Aromatase Inhibitors - therapeutic use
Chorionic Gonadotropin - therapeutic use
Clomiphene - therapeutic use
Follicle Stimulating Hormone, Human - therapeutic use
Humans
Hyperprolactinemia - complications
Hyperprolactinemia - diagnosis
Hypogonadism - complications
Hypogonadism - diagnosis
Infertility, Male - drug therapy
Infertility, Male - etiology
Male
Medicine
Medicine & Public Health
Menotropins - therapeutic use
Men’s Health (A Dabaja
Nephrology
Obesity - complications
Reproductive Control Agents - therapeutic use
Section Editor
Selective Estrogen Receptor Modulators - therapeutic use
Tamoxifen - therapeutic use
Thyroid Diseases - complications
Thyroid Diseases - diagnosis
Topical Collection on Men’s Health
Urology
Hormone-based therapies
Azoospermia
Clomiphene citrate
Male infertility
Human chorionic gonadotropin
Aromatase inhibitors
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Summary:Subfertility is defined as the condition of being less than normally fertile though still capable of effecting fertilization. When these subfertile couples seek assistance for conception, a thorough evaluation of male endocrine function is often overlooked. Spermatogenesis is a complex process where even subtle alterations in this process can lead to subfertility or infertility. Male endocrine abnormalities may suggest a specific diagnosis contributing to subfertility; however, in many patients, the underlying etiology is still unknown. Optimizing underlying endocrine abnormalities may improve spermatogenesis and fertility. This manuscript reviews reproductive endocrine abnormalities and hormone-based treatments.
Bibliography:ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-3
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ObjectType-Review-1
ISSN:1527-2737
1534-6285
DOI:10.1007/s11934-016-0612-4