Coronary CT Angiography Derived Fractional Flow Reserve: The Game Changer in Noninvasive Testing
Purpose of Review To summarize the scientific basis of CT derived fractional flow reserve (FFR CT ) and present an updated review on the evidence from clinical trials and real-world observational data Recent Findings In prospective multicenter studies of patients with stable coronary artery disease...
Saved in:
Published in | Current cardiology reports Vol. 19; no. 11; p. 112 |
---|---|
Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
New York
Springer US
01.11.2017
|
Subjects | |
Online Access | Get full text |
Cover
Loading…
Summary: | Purpose of Review
To summarize the scientific basis of CT derived fractional flow reserve (FFR
CT
) and present an updated review on the evidence from clinical trials and real-world observational data
Recent Findings
In prospective multicenter studies of patients with stable coronary artery disease (CAD), FFR
CT
showed high diagnostic performance. More recently, FFR
CT
has advanced to the realm of clinical utility and real-world clinical practice with emerging data showing that FFR
CT
when compared to standard care is efficient in safely reducing downstream utilization of invasive coronary angiography (ICA), and costs, as well as improving the diagnostic yield of ICA. Moreover, FFR
CT
may broaden applicability of frontline coronary CTA testing to patients with high pre-test risk of CAD.
Summary
Introducing FFR
CT
into clinical practice has the potential to significantly improve the management of patients with stable CAD. The optimal FFR
CT
testing interpretation strategy, as well as the relative cost-efficiency of FFR
CT
against standard noninvasive functional testing, need further investigation. |
---|---|
Bibliography: | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-3 content type line 23 ObjectType-Review-1 |
ISSN: | 1523-3782 1534-3170 |
DOI: | 10.1007/s11886-017-0923-1 |