Pancreatic pain

• Published in: Wiener medizinische Wochenschrift Vol. 164; no. 3-4; pp. 63 - 72
• Main Authors: Nechutova, Hana, Dite, Petr, Hermanova, Marketa, Novotny, Ivo, Martinek, Arnost, Klvana, Pavel, Kianicka, Bohumil, Soucek, Miroslav
• Format: Journal Article
• Language: English
• Published: Vienna Springer Vienna 01.02.2014
• Subjects: Chronic Pain - physiopathology; Chronic Pain - therapy; Family Medicine; General Practice; Geriatrics/Gerontology; Humans; Infectious Diseases; Inflammation Mediators - metabolism; Internal Medicine; Main Topic; Medicine; Medicine & Public Health; Neuralgia - physiopathology; Neuralgia - therapy; Neuronal Plasticity - physiology; Neurotransmitter Agents - physiology; Nociceptors - physiology; Pain Management - methods; Pancreas - innervation; Pancreatic Diseases - physiopathology; Pancreatic Diseases - therapy; Pancreatitis, Chronic - physiopathology; Pancreatitis, Chronic - therapy; Pharmacology/Toxicology; Noziceptive; Stratification of analgesic treatment; Neuropathische; Neuroplastic changes; Neuropathic and inflammatory pain; Neuromodulation; Nociceptive; Inflammatorische Schmerzkomponente; Pain in pancreatopathies; Schmerz bei Pankreaserkrankungen; Stratifikation der Schmerztherapie; Pain; Neuroplastische Veränderungen; Schmerz; Sensitization; Schmerzempfindung
• ISSN: 0043-5341; 1563-258X
• DOI: 10.1007/s10354-014-0265-1

Summary Pain is a common symptom of many diseases. Recently, the pain has been classified and analyzed exactly. Its particular components/types are described to the maximum of their depths and details. That is why each particular pain present in a specific disease (pancreatopathies included) has to be treated according to the presence of the specific type of pain. In diseases of pancreas, there are nociceptive, neuropathic, and inflammatory components of pain participating, frequently. Especially long-lasting, not well-controlled pain sets off the process of neuromodulation. The recent pioneering applications/administrations of various neuromodulatory therapeutic approaches represent the promising discoveries for the treatment of long-term, severe, drug-resistant pain syndromes, including chronic pancreatitis. In this article, we summarized the characteristics of pain, the therapeutic strategy, and algorithms of analgesic treatment (in general and applied for pancreatopathies), including new therapeutic trends and approaches.