Instability of bronchial epithelium in chronic pulmonary diseases

Pathomorphological examination of large bronchi in patients with occupational diseases, lung cancer, and in subjects exposed to radiation revealed structural and functional heterogeneity of the epithelium: the presence of focal atrophy, metaplasia, hyper- and dysplasia in the same biopsy specimen. T...

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Bibliographic Details
Published inBulletin of experimental biology and medicine Vol. 129; no. 4; pp. 396 - 399
Main Authors Nepomnyashchikh, G I, Levitskii, V A, Nepomnyashchikh, L M, Aidagulova, S V, Naumova, L A, Belov, I Y
Format Journal Article
LanguageEnglish
Published United States Springer Nature B.V 01.04.2000
Subjects
Autoradiography
Bronchi - pathology
Cell Division
Chronic Disease
Epithelial Cells - pathology
Humans
Lung Diseases - pathology
Medical research
Occupational diseases
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Summary:Pathomorphological examination of large bronchi in patients with occupational diseases, lung cancer, and in subjects exposed to radiation revealed structural and functional heterogeneity of the epithelium: the presence of focal atrophy, metaplasia, hyper- and dysplasia in the same biopsy specimen. This phenomenon was termed as instability of the epithelium. Thickness of the epithelium greatly varied, especially, in neoplastic processes. Atrophy and epithelial instability phenomenon are interpreted as morphological markers of ecological and oncological risk.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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ISSN:0007-4888
1573-8221
DOI:10.1007/BF02439282