Quantitative hemoglobin tomography with diffuse near-infrared spectroscopy: pilot results in the breast

The authors describe what is, to the best of their knowledge, the first quantitative hemoglobin concentration images of the female breast that were formed with model-based reconstruction of near-infrared intensity-modulated tomographic data. The results in 11 patients, including two with breast tumo...

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Bibliographic Details
Published inRadiology Vol. 218; no. 1; p. 261
Main Authors Pogue, B W, Poplack, S P, McBride, T O, Wells, W A, Osterman, K S, Osterberg, U L, Paulsen, K D
Format Journal Article
LanguageEnglish
Published United States 01.01.2001
Subjects
Adult
Breast
Breast Neoplasms - diagnosis
Carcinoma, Ductal, Breast - diagnosis
Equipment Design
Female
Fibroadenoma - diagnosis
Hemoglobins - analysis
Humans
Middle Aged
Pilot Projects
Spectroscopy, Near-Infrared
Tomography - instrumentation
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Summary:The authors describe what is, to the best of their knowledge, the first quantitative hemoglobin concentration images of the female breast that were formed with model-based reconstruction of near-infrared intensity-modulated tomographic data. The results in 11 patients, including two with breast tumors with pathologic correlation, are summarized. Hemoglobin concentration appears to correlate with tumor vascularity without the need for exogenous contrast material and thereby has intrinsic diagnostic value.
ISSN:0033-8419
DOI:10.1148/radiology.218.1.r01ja51261