The estimation of the possibilities of synchrotron radiation X-ray fluorescent analysis and atomic specrometry for the bone's elemental composition determination

• Published in: Nuclear instruments & methods in physics research. Section A, Accelerators, spectrometers, detectors and associated equipment Vol. 543; no. 1; pp. 271 - 273
• Main Authors: Gonchar, A.M., Kolmogorov, U.P., Gladkikh, E.A., Shuvaeva, O.V., Beisel, N.F., Kolosova, N.G.
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.05.2005
• Subjects: AAS; Bone; Elemental composition; IBP AES; RFA SR; 07.85.Qe; AAS; 89.60+x; RFA SR; Elemental composition; IBP AES; Bone
• ISSN: 0168-9002; 1872-9576
• DOI: 10.1016/j.nima.2005.01.239

Possibilities of multielemental highly sensitive techniques of analysis have been studied: synchrotron radiation X-ray fluorescence analysis (SR XFA), and atomic emission spectrometry with inductively bound plasma (ISP) and atomic absorption spectrometry (AAS) with flame (air–acetylene) atomization for assay of element composition of bone tissue with minimal preparation procedure. Results of comparative studies of elemental composition of bone tissue samples from experimental animals with inherited accelerated aging (rats of OXYS strain) using the SR XFA, ISP and AAS techniques are presented. It is shown that there exists in principle a possibility of assay of 22 biologically important essential macro- and trace elements within the range of 1.0–100,000 μg/g with a mean square analysis error of no more them 10–15% when using SR XFA.