Relationship of HLA-B51 and HLA-B52 alleles and TNF-α-308A/G polymorphism with susceptibility to Takayasu arteritis: a meta-analysis

• Published in: Clinical rheumatology Vol. 36; no. 1; pp. 173 - 181
• Main Authors: Chen, Si, Luan, Haixia, Li, Liubing, Zeng, Xiaoli, Wang, Tian, Li, Yongzhe, Yuan, Hui
• Format: Journal Article
• Language: English
• Published: London Springer London 01.01.2017
• Subjects: Alleles; Case-Control Studies; Genetic Predisposition to Disease; Genotype; HLA-B51 Antigen - genetics; HLA-B52 Antigen - genetics; Humans; Inflammation; Medicine; Medicine & Public Health; Original Article; Polymorphism, Genetic; Rheumatology; Sensitivity and Specificity; Takayasu Arteritis - genetics; Tumor Necrosis Factor-alpha - genetics; Takayasu arteritis; TNF-α; HLA; Meta-analysis; Polymorphism

We performed a meta-analysis to determine whether combined evidence shows an association between HLA-B*51 and HLA-B*52 alleles and TNF-α-308A/G polymorphism and the susceptibility to Takayasu arteritis (TA). Relevant articles dated November 2015 were acquired from the PubMed, Embase and Cochrane dat...