Isolation and Structural Determination of a Novel Antimicrobial Compound from the Root of Pulsatilla koreana

A new antimicrobial pulsaquinone (1), having a novel 7-6 bicyclic carbon skeleton, was isolated from the root of Pulsatilla koreana Nakai. The structure was established by its MS, 1 H-, 13 C-, and two dimensional NMR ( 1 H- 1 H COSY and HMBC) spectroscopic data and confirmed by the selective reducti...

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Published inNatural product letters Vol. 14; no. 4; pp. 311 - 317
Main Authors Moon, Jae-Hak, Ma, Seung-Jin, Lee, Hyang-Hee, Watanabe, Naoharu, Yagi, Akihito, Sakata, Kanzo, Park, Keun-Hyung
Format Journal Article
LanguageEnglish
Published Taylor & Francis Group 01.07.2000
Subjects
7-6 bicyclic carbon skeleton
Antimicrobial compound
Pulsadiol
Pulsaquinone
Pulsatilla koreana
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Summary:A new antimicrobial pulsaquinone (1), having a novel 7-6 bicyclic carbon skeleton, was isolated from the root of Pulsatilla koreana Nakai. The structure was established by its MS, 1 H-, 13 C-, and two dimensional NMR ( 1 H- 1 H COSY and HMBC) spectroscopic data and confirmed by the selective reduction of 1.
ISSN:1057-5634
DOI:10.1080/10575630008041248